Concern

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As a result of your final answer.

That is my 2nd time we delivered this concern.

I have re-done a research that is thorough the structure of male genitalia. In a nutshell, it turns out that information out there was inconsistent. In Wikipedia, two split entries of Foreskin’ and Mucous membrane’ yield contradictory outcomes: the previous states the glans penis (head of this penis) and glans clitoridis plus the inside the prepuce (foreskin) and clitoral bonnet are maybe maybe not mucous membranes’, whilst the latter says that the internal foreskin is just a mucous membrane layer just like the inside the eyelid or even the lips. ‘ in addition, in accordance with glans penis’ of wikipedia, The epithelium associated with the glans penis is mucocutaneous muscle.’

By the means we learned that the foreskin consists of Langerhans cells that are recognized as receptor of HIV virus (these details arises from OU Handbook of GUM and HIV medicine).

I’ve talked about these problems with a psychiatrist (the reason being that i’m i am exceedingly concerned throughout the whole HIV/STD thingy) who warned me personally that i ought ton’t be doing penis-to-penis side-along rubbing and penis docking more because `it’s rubbing of mucosal cells. HIV/STD virus is likely to pass between. Why can you just simply take such risks?’

In your final answer (answer that is final), you said that the transmission chance of dick-docking is actually nonexistent and implied that penis-to-penis side-along rubbing does perhaps perhaps not pose any transmission danger as the only mucous membrane for the entire cock (including shaft, foreskin, glans penis) may be the liner regarding the urethra through the pee-hole up to your bladder. But i did not point out that i am uncircumcised. There is a good amount of internal foreskin whose extremely nature is very dubious of mucous membrane and which can be saturated in Langerhans cells.

Therefore my questions are: (1) might you please reiterate your viewpoint regarding the transmission chance of dick-docking and penis-to-penis side-along rubbing, citing the reason for?? let’s say certainly one of us shot charmdate Seznamka the strain? Would the strain shoot right at the urethra during docking. (2) should we put for a condom although we do dick-docking and penis-to-penis side-along rubbing? (3) must I do a circumcision, as some studies from Kenya(!) recommend it decreases the possibility of transmission of HIV along with other STDs? Do you think it?? (4) exactly why are Langerhans cells cited as vunerable to HIV infection? Just just What part does it play ?? (5) how come the word membrane that is `mucous so essential in HIV illness? The facts anyhow?? Would HIV or other STDs have throughout the membrane layer and infect other people??

As bothersome as i will be, I sincerely do hope that you’dn’t find my inquiries unpleasant or devious at all. Debate contributes to better understanding. In an effort you painstakingly answer my questions? for me to have some sort of peace, could?

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Response

My estimation regarding HIV transmission/acquisition associated to frottage (penis-to-penis rubbing, “dick-docking”) remains unchanged. It’s not regarded as being a danger. Could you shoot lots and strike the urethra? Yes, it is theoretically feasible, while not more than likely, that the spunk would really enter into significant connection with the urethra’s mucous membrane layer.

If that will make you are feeling safer much less anxious, yes. Individually, I do not feel it really is necessary.

The studies do indicate that male circumcision decreases the danger for acquiring HIV. But, in the event that you follow safer intimate practices, I don’t feel it really is necessary.

Langerhan’s cells (dendritic cells) perform a role that is important the initiation of HIV disease by virtue for the cap ability of HIV to bind to particular cellular area receptors of the cells. This permits presentation that is efficient of to CD4 cells that then become contaminated. The foreskin contains Langerhan’s cells.

A mucous membrane layer is a slim layer (membrane) that lines all interior human anatomy passages that communicate straight with atmosphere beyond your human body, like the breathing and alimentary tracts, and that has specialized cells or glands that secrete mucous. HIV can permeate mucous membranes, however it cannot permeate intact epidermis. The foreskin is certainly not a mucous membrane layer. But, it really is a specific style of epidermis and HIV could be taken on because of the Langerhan’s (dendritic) cells situated inside the foreskin.

We undoubtedly do not find your inquiries either devious or”offensive.” It could be somewhat confusing to try and explain complex information on structure or the purpose of specific cells in a forum like this forum. And so the physiology class is finished for today.